OptimalHealthNutrition.com

 

 
 

Update: Please see the new website at HealGrowThriveMedicine.com

  



Shopping cart  Shopping cart
0 Product(s) in cart
Total $0.00
» Checkout

Valid XHTML 1.0 Transitional

© Copyright 2008
Shopping cart software by Ecommerce Templates

 

Eicosanoids
Research News: The general term “eicosanoids” is used to describe the various metabolic end products of 20-carbon fatty acid metabolism, including thromboxanes (TX), leukotrienes (LT), and prostaglandins (PG). Produced in minute quantities of approximately 1 milligram per day[1], prostaglandins are produced by nearly all mammalian cells; their production is not confined to leukocytes even though they are often associated with immune activation. Since they are produced and act locally at the site of metabolic activation, they are autocrine and paracrine rather than endocrine.[2] These chemicals have short half-lives, with thromboxanes existing only for a few seconds after production[3] while leukotrienes persist for as long as four hours.[4] While specific enzymes transform one fatty acid into another (within the same family, n-3 or n-6, respectively), the production of eicosanoids is initiated by enzymes but often completed by non-specific, random interactions dependent on free radicals and/or random conformational changes in enzymes and substrates.[5]



----------------------



[1] Delvin TM. Textbook of Biochemistry with Clinical Correlations. New York: Wiley-Liss, 1997. Pages 431-441

[2] McGlivery RW. Biochemistry: A Functional Approach. Third Edition. Philadelphia: WB Saunders, 1983. Pages 747-750

[3] McGlivery RW. Biochemistry: A Functional Approach. Third Edition. Philadelphia: WB Saunders, 1983. Pages 747-750

[4] Delvin TM. Textbook of Biochemistry with Clinical Correlations. New York: Wiley-Liss, 1997. Pages 431-441

[5] Thuresson ED, Lakkides KM, Smith WL. Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products. J Biol Chem. 2000 Mar 24;275(12):8501-7 Available on-line at http://www.jbc.org/cgi/reprint/275/12/8501 as of December 28, 2003.

 
Dr Vasquez's Comments: This is an excerpt from my textbook "Chiropractic and Naturopathic Mastery of Common Clinical Disorders" which is available from OptimalHealthResearch.com (website with clinical information designed for doctors) and also from OptimalHealthNutrition.com in our selection of books.

DOCTORS: See Optimal Health Research for textbooks and clinical protocols!

 

 

 

 

 

 

See our new site at AntiCancer Cookbook.com -- coming soon!

 
       

All Products | Browse Items | Search Items | Secure Ordering | Customer Entrance | eNews, Audio MP3 Videos & PodCasts | About | Site Contents | Community Links | Consult Dr Vasquez

OptimalHealthNutrition.com provides information for patients and the general public, while OptimalHealthResearch.com provides information for medical/chiropractic/osteopathic/naturopathic students and doctors. These sites are owned by Integrative and Biological Medicine Research and Consulting LLC (IBMRC).  Copyright 2009 by IBMRC and/or Dr Alex Vasquez.  All rights reserved.  Use of this site implies agreement with our Terms & Agreements.  Caution: Bee products may cause allergic reactions in some people. Due to honey content, not recommended for children under two years of age. These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.